The compatibility of the material to build microfluidic devices was evaluated in three different ways (1) determining if the UV cured resin inhibits the polymerase chain reaction (PCR) i.e., testing devices for PCR compatibility and (2) observing agglutination complex formed on the surface of the UV cured resin when anti-CRP antibodies and Creactive protein (CRP) proteins were allowed to agglutinate (3) by culturing human embryonic kidney cell line (HEK) cells and testing for its attachment and viability. This study finds importance in building Lab-on-chip/Micro Total analysis systems (µTAS) and organ-on-chip devices.
This work is a collaboration with prof. Niveen Khashab. This work was first presented at NEMS 2016 and was invited for a special issue at the IET Micro and Nano letter. More details can be found at
Shilpa Sivashankar, Sumeyra Agambayev, kholod alamoudi, Ulrich Buttner,Niveen Khashab, and Khaled Nabil Salama Compatibility analysis of 3D printer resin for biological applications, micro and nano letters, 2016
Shilpa Sivashankar, Sumeyra Agambayev, Ulrich Buttner, Khaled Nabil Salama, Characterization of Solid UV Curable 3D Printer Resins for Biological Applications, NEMS2016