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The hunt for rapid early cancer detection

posted Aug 26, 2017, 8:25 AM by Khaled salama   [ updated Aug 26, 2017, 8:26 AM ]
An in vitro diagnostic, biosensor-CMOS platform was developed to screen and quantify SSAT enzyme for rapid early detection of cancer, which dramatically improves the survival rate of cancer patients. A large sensing area with small baseline capacitance was introduced to implement a capacitive biosensor that shows a high sensitivity to SSAT enzyme concentrations. 
PhD Student Abdulaziz Alhoshany developed a successive readout circuit incorporating a clocked inverter-based SAR architecture was introduced to read and process the information from the biosensor.  The diagnostic platform can be miniaturized into a complete microsystem in a compact size by integrating the sensing electrode and the associated readout circuit in a single tiny package. Therefore, the miniaturized device can be produced in low-cost, small size, and mass-production technology compared to state of the art.  You can read all about it at:
Alhoshany, A.; Sivashankar, S.; Mashraei, Y.; Omran, H.; Salama, K.N. A Biosensor-CMOS Platform and Integrated Readout Circuit in 0.18-μm CMOS Technology for Cancer Biomarker DetectionSensors 201717, 1942.